Epigenetic suppression of E-cadherin expression by Snail2 during the metastasis of colorectal cancer

Abstract Background The transcription factor Snail2 is a repressor of E-cadherin expression during carcinogenesis; however, the specific mechanisms involved in this process in human colorectal cancer (CRC) remain largely unknown. Method We checked the expression of Snail2 in several clinical CRC spe...

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Bibliographic Details
Main Authors: Yue Hu, Mingrui Dai, Yayuan Zheng, Jiaxin Wu, Bin Yu, Haihong Zhang, Wei Kong, Hui Wu, Xianghui Yu
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Clinical Epigenetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13148-018-0592-y