NLRP3 inflammasome activation mediates sleep deprivation-induced pyroptosis in mice

Background Sleep deprivation (SD) has many deleterious health effects, including cognitive decline, work ability decline, inadequate alertness, etc. Neuroinflammation plays an important role in sleep deprivation. However, the underlying mechanism is still unclear. Methods In the present study, we de...

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Bibliographic Details
Main Authors: Kun Fan, Jiajun Yang, Wen-Yi Gong, Yong-Chao Pan, Peibing Zheng, Xiao-Fang Yue
Format: Article
Language:English
Published: PeerJ Inc. 2021-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/11609.pdf