Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence [version 2; peer review: 2 approved]

Background: Blockade of the cytokine interleukin-1 (IL-1) with IL-1 receptor antagonist (IL-1Ra) is a candidate treatment for stroke entering phase II/III trials, which acts by inhibiting harmful inflammatory responses.  Infection is a common complication after stroke that significantly worsens outc...

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Bibliographic Details
Main Authors: Laura McCulloch, Stuart M. Allan, Hedley C. Emsley, Craig J. Smith, Barry W. McColl
Format: Article
Language:English
Published: F1000 Research Ltd 2019-10-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-1039/v2