Effects of intrahippocampal administration of the phosphatase inhibitor okadaic acid: Dual effects on memory formation

Abstract Protein phosphorylation mediated by serine-threonine kinases in the hippocampus is crucial to the synaptic modifications believed to underlie memory formation. The role of phosphatases has been the focus of comparatively little study. Objectives: Here we evaluate the contribution of the ser...

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Bibliographic Details
Main Authors: Monica R.M. Vianna, Adriana Coitinho, Luciana Izquierdo, Ivan Izquierdo
Format: Article
Language:English
Published: Associação Neurologia Cognitiva e do Comportamento
Series:Dementia & Neuropsychologia
Subjects:
PP1
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642010000100023&lng=en&tlng=en