Histopathologic-molecular Correlation in Early Mycosis Fungoides Using T-cell Receptor γ Gene Rearrangement by Polymerase Chain Reaction with Laser Capture Microdissection

Histopathologic-molecular Correlation in Early Mycosis Fungoides Using T-cell Receptor γ Gene Rearrangement by Polymerase Chain Reaction with Laser Capture Microdissection

Early mycosis fungoides (MF) is difficult to distinguish from other benign inflammatory dermatoses. We evaluated clonal T-cell receptor (TCR) γ Gene rearrangement by polymerase chain reaction (PCR) as a surrogate to histologic diagnosis in early MF. Methods: Twenty paraffin-embedded skin biopsies fr...

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Bibliographic Details
Main Authors: Pa-Fan Hsiao, Cheng-Hsiang Hsiao, Yang-Chih Lin, Mei-Ping Tseng, Tsen-Fang Tsai, Shiou-Hwa Jee
Format: Article
Language:English
Published: Elsevier 2007-01-01
Series:Journal of the Formosan Medical Association
Subjects:
laser capture microdissection
mycosis fungoides
polymerase chain reaction
T-cell receptor γ Gene rearrangement
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664609602515

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http://www.sciencedirect.com/science/article/pii/S0929664609602515

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