Self-oligomerization is essential for enhanced immunological activities of soluble recombinant calreticulin.

Self-oligomerization is essential for enhanced immunological activities of soluble recombinant calreticulin.

We have recently reported that calreticulin (CRT), a luminal resident protein, can be found in the sera of patients with rheumatoid arthritis and also that recombinant CRT (rCRT) exhibits extraordinarily strong immunological activities. We herein further demonstrate that rCRT fragments 18-412 (rCRT/...

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Bibliographic Details
Main Authors: Shang-Hui Huang, Li-Xiang Zhao, Chao Hong, Cui-Cui Duo, Bing-Nan Guo, Li-Juan Zhang, Zheng Gong, Si-Dong Xiong, Fang-Yuan Gong, Xiao-Ming Gao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3677884?pdf=render

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http://europepmc.org/articles/PMC3677884?pdf=render

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