Intestinal Permeability Is a Mechanical Rheostat in the Pathogenesis of Liver Cirrhosis

Intestinal Permeability Is a Mechanical Rheostat in the Pathogenesis of Liver Cirrhosis

Recent studies have suggested that an alteration in the gut microbiota and their products, particularly endotoxins derived from Gram-negative bacteria, may play a major role in the pathogenesis of liver diseases. Gut dysbiosis caused by a high-fat diet and alcohol consumption induces increased intes...

Full description

Bibliographic Details
Main Authors: Norihisa Nishimura, Kosuke Kaji, Koh Kitagawa, Yasuhiko Sawada, Masanori Furukawa, Takahiro Ozutsumi, Yukihisa Fujinaga, Yuki Tsuji, Hiroaki Takaya, Hideto Kawaratani, Kei Moriya, Tadashi Namisaki, Takemi Akahane, Hiroshi Fukui, Hitoshi Yoshiji
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
leaky gut
endotoxins
alcoholic liver disease
nonalcoholic steatohepatitis
liver cirrhosis
hepatocarcinogenesis
Online Access:https://www.mdpi.com/1422-0067/22/13/6921

Internet

https://www.mdpi.com/1422-0067/22/13/6921

Similar Items