Tyrosine Kinase Inhibitors Could Be Effective Against Non-small Cell Lung Cancer Brain Metastases Harboring Uncommon EGFR Mutations

Tyrosine Kinase Inhibitors Could Be Effective Against Non-small Cell Lung Cancer Brain Metastases Harboring Uncommon EGFR Mutations

Background: The significance of uncommon epidermal growth factor receptor (EGFR) mutations in patients with non-small cell lung cancer (NSCLC) and brain metastasis (BM) remains unclear. Cerebrospinal fluid (CSF) liquid biopsy is a novel tool for assessing EGFR mutations in BM. This study aimed to ev...

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Bibliographic Details
Main Authors: Chunhua Ma, Juncheng Zhang, Dongjiang Tang, Xin Ye, Jing Li, Ning Mu, Zhi Li, Renzhong Liu, Liang Xiang, Chuoji Huang, Rong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer
brain metastasis
tyrosine kinase inhibitors
epidermal growth factor receptor
mutation
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00224/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00224/full

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