Diagnosis of Acute Lymphoblastic Leukemia Originating From T-Lineage Precursors and Approaches to Minimal Residual Disease Monitoring

Diagnosis of Acute Lymphoblastic Leukemia Originating From T-Lineage Precursors and Approaches to Minimal Residual Disease Monitoring

Background. Minimal residual disease (MRD) is an independent prognostic factor in acute lymphoblastic leukemia (ALL) in children. The immunological assessment of MRD cell count is based on aberrant immunophenotype of tumor lymphoblasts. However, in the case of ALL originating from T-lineage precurso...

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Bibliographic Details
Main Authors: OA Chernysheva, LYu Grivtsova, IN Serebryakova, NA Kupryshina, EN Sholokhova, MA Shervashidze, AD Palladina, BV Kurdyukov, AV Popa, NN Tupitsyn
Format: Article
Language:Russian
Published: Practical Medicine Publishing House 2018-12-01
Series:Kliničeskaâ onkogematologiâ
Subjects:
T-lineage acute lymphoblastic leukemia
multicolor flow cytometry
minimal residual disease
leukemia-associated immunophenotype
Online Access:http://bloodjournal.ru/en/diagnosis-of-acute-lymphoblastic-leukemia-originating-from-t-lineage-precursors-and-approaches-to-minimal-residual-disease-monitoring/

Internet

http://bloodjournal.ru/en/diagnosis-of-acute-lymphoblastic-leukemia-originating-from-t-lineage-precursors-and-approaches-to-minimal-residual-disease-monitoring/

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