In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.

In vivo antiviral host transcriptional response to SARS-CoV-2 by viral load, sex, and age.

Despite limited genomic diversity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has shown a wide range of clinical manifestations in different patient populations. The mechanisms behind these host differences are still unclear. Here, we examined host response gene expression across i...

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Bibliographic Details
Main Authors: Nicole A P Lieberman, Vikas Peddu, Hong Xie, Lasata Shrestha, Meei-Li Huang, Megan C Mears, Maria N Cajimat, Dennis A Bente, Pei-Yong Shi, Francesca Bovier, Pavitra Roychoudhury, Keith R Jerome, Anne Moscona, Matteo Porotto, Alexander L Greninger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000849

Internet

https://doi.org/10.1371/journal.pbio.3000849

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