Paclitaxel Through the Ages of Anticancer Therapy: Exploring Its Role in Chemoresistance and Radiation Therapy

Paclitaxel (Taxol®) is a member of the taxane class of anticancer drugs and one of the most common chemotherapeutic agents used against many forms of cancer. Paclitaxel is a microtubule-stabilizer that selectively arrests cells in the G2/M phase of the cell cycle, and found to induce cytotoxicity in...

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Bibliographic Details
Main Authors: Anna Maria Barbuti, Zhe-Sheng Chen
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/7/4/0897