Knowledge-guided multi-scale independent component analysis for biomarker identification

<p>Abstract</p> <p>Background</p> <p>Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical methods often fail to identify biologically meaningful biomarkers...

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Bibliographic Details
Main Authors: Zhang Zhen, Wang Yue, Shih Ie-Ming, Wang Chen, Xuan Jianhua, Chen Li, Hoffman Eric, Clarke Robert
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/416