KALRN mutations promote antitumor immunity and immunotherapy response in cancer

Background kalirin RhoGEF kinase (KALRN) is mutated in a wide range of cancers. Nevertheless, the association between KALRN mutations and the pathogenesis of cancer remains unexplored. Identification of biomarkers for cancer immunotherapy response is crucial because immunotherapies only show benefic...

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Bibliographic Details
Main Authors: Mengyuan Li, You Zhong, Canping Chen, Lei Qiang, Xiaosheng Wang
Format: Article
Language:English
Published: BMJ Publishing Group 2020-07-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000293.full