Regulation of CD4 Receptor and HIV-1 Entry by MicroRNAs-221 and -222 during Differentiation of THP-1 Cells

Human immunodeficiency virus type-1 (HIV-1) infection of monocyte/macrophages is modulated by the levels of entry receptors cluster of differentiation 4 (CD4) and C-C chemokine receptor type 5 (CCR5), as well as by host antiviral restriction factors, which mediate several post-entry blocks. We recen...

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Bibliographic Details
Main Authors: Robert Lodge, Julian C. Gilmore, Jérémy A. Ferreira Barbosa, Félix Lombard-Vadnais, Éric A. Cohen
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/10/1/13