B-cell depletion therapy for multiple sclerosis

Since the initial observation of increased immunoglobulin concentrations in the cerebrospinal fluid of multiple sclerosis (MS) patients in the 1940s, B cells have been considered to participate in the pathology of MS through the production of autoantibodies reactive against central nervous system an...

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Bibliographic Details
Main Authors: Yusei Miyazaki, Masaaki Niino
Format: Article
Language:English
Published: Taylor & Francis Group 2021-07-01
Series:Immunological Medicine
Subjects:
Online Access:http://dx.doi.org/10.1080/25785826.2021.1952543