Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells

Allopregnanolone Alters the Gene Expression Profile of Human Glioblastoma Cells

Glioblastomas (GBM) are the most frequent and aggressive brain tumors. In these malignancies, progesterone (P4) promotes proliferation, migration, and invasion. The P4 metabolite allopregnanolone (3α-THP) similarly promotes cell proliferation in the U87 human GBM cell line. Here, we evaluated global...

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Bibliographic Details
Main Authors: Carmen J. Zamora-Sánchez, Aylin del Moral-Morales, Ana M. Hernández-Vega, Valeria Hansberg-Pastor, Ivan Salido-Guadarrama, Mauricio Rodríguez-Dorantes, Ignacio Camacho-Arroyo
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:International Journal of Molecular Sciences
Subjects:
allopregnanolone
progesterone metabolites
finasteride
astrocytomas
glioblastomas
Online Access:http://www.mdpi.com/1422-0067/19/3/864

Internet

http://www.mdpi.com/1422-0067/19/3/864

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