The Complexity of the Tumor Microenvironment and Its Role in Acute Lymphoblastic Leukemia: Implications for Therapies

The microenvironment that surrounds a tumor, in addition to the tumor itself, plays an important role in the onset of resistance to molecularly targeted therapies. Cancer cells and their microenvironment interact closely between them by means of a molecular communication that mutually influences the...

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Bibliographic Details
Main Authors: Carolina Simioni, Ilaria Conti, Gabriele Varano, Cinzia Brenna, Eva Costanzi, Luca M. Neri
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Oncology
Subjects:
ALL
HIF
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.673506/full