CK2 Molecular Targeting—Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer

CK2 Molecular Targeting—Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer

Protein kinase CK2 demonstrates increased protein expression relative to non-transformed cells in the majority of cancers that have been examined. The elevated levels of CK2 are involved in promoting not only continued proliferation of cancer cells but also their resistance to cell death; thus, CK2...

Full description

Bibliographic Details
Main Authors: Janeen H. Trembley, Betsy T. Kren, Md. Joynal Abedin, Rachel I. Vogel, Claire M. Cannon, Gretchen M. Unger, Khalil Ahmed
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Pharmaceuticals
Subjects:
CK2
nanocapsules
nanoparticles
anti-CK2
RNAi
siRNA
tenfibgen
TBG
TBG-RNAi-CK2
therapy
cancer
targeting
cancer-specific
tumor-specific
prostate cancer
breast cancer
HNSCC
Online Access:http://www.mdpi.com/1424-8247/10/1/25

Internet

http://www.mdpi.com/1424-8247/10/1/25

Similar Items