Clinically useful limited sampling strategy to estimate area under the concentration-time curve of once-daily tacrolimus in adult Japanese kidney transplant recipients.

Clinically useful limited sampling strategy to estimate area under the concentration-time curve of once-daily tacrolimus in adult Japanese kidney transplant recipients.

BACKGROUND:An extended-release, once-daily, oral formulation of tacrolimus is currently used after kidney transplantation as a substitute for the conventional twice-daily formulation. The purpose of this study was to provide a limited sampling strategy with minimum and optimum sampling points to pre...

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Bibliographic Details
Main Authors: Ryuto Nakazawa, Miki Yoshiike, Shiari Nozawa, Koichiro Aida, Yuichi Katsuoka, Eisuke Fujimoto, Masahiko Yazawa, Eiji Kikuchi, Yugo Shibagaki, Hideo Sasaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225878

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https://doi.org/10.1371/journal.pone.0225878

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