A virus-acquired host cytokine controls systemic aging by antagonizing apoptosis.

Aging is characterized by degeneration of unique tissues. However, dissecting the interconnectedness of tissue aging remains a challenge. Here, we employ a muscle-specific DNA damage model in Drosophila to reveal secreted factors that influence systemic aging in distal tissues. Utilizing this model,...

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Bibliographic Details
Main Authors: Mohamed Mlih, Mobina Khericha, Christine Birdwell, A Phillip West, Jason Karpac
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2005796