NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence

NCOR1 Sustains Colorectal Cancer Cell Growth and Protects against Cellular Senescence

NCOR1 is a corepressor that mediates transcriptional repression through its association with nuclear receptors and specific transcription factors. Some evidence supports a role for NCOR1 in neonatal intestinal epithelium maturation and the maintenance of epithelial integrity during experimental coli...

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Bibliographic Details
Main Authors: Stéphanie St-Jean, Ariane Cristina De Castro, Mia Lecours, Christine Jones, Nathalie Rivard, Francis Rodier, Nathalie Perreault, François Boudreau
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
NCOR1
intestinal tumorigenesis
Caco-2/15
HT-29
senescence
<i>Apc<sup>Min/+</sup></i>
Online Access:https://www.mdpi.com/2072-6694/13/17/4414

Internet

https://www.mdpi.com/2072-6694/13/17/4414

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