miR-155 antagomir protect against DSS-induced colitis in mice through regulating Th17/Treg cell balance by Jarid2/Wnt/β-catenin

miR-155 antagomir protect against DSS-induced colitis in mice through regulating Th17/Treg cell balance by Jarid2/Wnt/β-catenin

Background: Th subsets particularly T helper 17 and regulatory T cells play a critical role in immune balance in colonic mucosa of Inflammatory Bowel Disease. Recent studies have indicated miR-155 is overexpressed in the colonic mucosa in IBD patients. Thus, whether and how miR-155 influences Th17/T...

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Bibliographic Details
Main Authors: Feng Zhu, Huarong Li, Yujin Liu, Chen Tan, Xingxing Liu, Heng Fan, Hui Wu, Yalan Dong, Ting Yu, Si Chu, Hongxia He, Xiwen Zhu
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
miR-155 antagomir
IBD
Th17/Treg cell balance
Jarid2
Wnt/β-catenin
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220300998

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http://www.sciencedirect.com/science/article/pii/S0753332220300998

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