Trehalose Reduces the Secreted Beta-Amyloid Levels in Primary Neurons Independently of Autophagy Induction

The disaccharide trehalose was described as possessing relevant neuroprotective properties as an mTORC1-independent inducer of autophagy, with the ability to protect cellular membranes and denaturation, resulting from desiccation, and preventing the cellular accumulation of protein aggregates. These...

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Bibliographic Details
Main Authors: Irene Benito-Cuesta, Lara Ordoñez-Gutierrez, Francisco Wandosell
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/7/421