Clinical and economic issues complicating cost-effectiveness evaluation of orphan diseases

Cost-effectiveness evaluation of orphan medicinal products is confronted with a large confidence interval on the incremental cost-effectiveness ratios (ICERs), or extremely high ICERs and therefore rejection of products for uptake in the health insurance package (coverage) by health authorities in E...

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Bibliographic Details
Main Authors: Nuijten Mark J.C., Pronk Marja H., Hutton John, Hasselt Peter van, Oosterwijk Cor, Rutten Frans F.H.
Format: Article
Language:English
Published: Sciendo 2017-05-01
Series:The EuroBiotech Journal
Online Access:https://doi.org/10.24190/ISSN2564-615X/2017/02.04