Decreased thyroid follicle size in dwarf mice may suggest the role of growth hormone signaling in thyroid growth regulation

Decreased thyroid follicle size in dwarf mice may suggest the role of growth hormone signaling in thyroid growth regulation

<p>Abstract</p> <p>Background</p> <p>Altered somatotrophic signaling is among the most important potential mechanisms of extended longevity. Ames dwarf (df/df) mice are homozygous for mutation at the Prop-1 gene, leading to a lack of growth hormone (GH), prolactin and t...

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Bibliographic Details
Main Authors: Gesing Adam, Bartke Andrzej, Masternak Michal M, Lewiński Andrzej, Karbownik-Lewińska Małgorzata
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Thyroid Research
Subjects:
Ames dwarf mice
GHRKO mice
Thyroid follicle
Inner follicular surface area
Inner follicular perimeter
Follicular epithelium thickness
Online Access:http://www.thyroidresearchjournal.com/content/5/1/7

Internet

http://www.thyroidresearchjournal.com/content/5/1/7

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