Resveratrol Prevents Right Ventricle Dysfunction, Calcium Mishandling, and Energetic Failure via SIRT3 Stimulation in Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vessel remodeling; however, its severity and impact on survival depend on right ventricular (RV) failure. Resveratrol (RES), a polyphenol found in red wine, exhibits cardioprotective effects on RV dysfunction in PAH. However, most l...

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Bibliographic Details
Main Authors: Judith Bernal-Ramírez, Christian Silva-Platas, Carlos Jerjes-Sánchez, Martín R. Ramos-González, Eduardo Vázquez-Garza, Héctor Chapoy-Villanueva, Alicia Ramírez-Rivera, Ángel Zarain-Herzberg, Noemi García, Gerardo García-Rivas
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/9912434