N-Acetylneuraminic Acid Supplementation Prevents High Fat Diet-Induced Insulin Resistance in Rats through Transcriptional and Nontranscriptional Mechanisms

N-Acetylneuraminic Acid Supplementation Prevents High Fat Diet-Induced Insulin Resistance in Rats through Transcriptional and Nontranscriptional Mechanisms

N-Acetylneuraminic acid (Neu5Ac) is a biomarker of cardiometabolic diseases. In the present study, we tested the hypothesis that dietary Neu5Ac may improve cardiometabolic indices. A high fat diet (HFD) + Neu5Ac (50 or 400 mg/kg BW/day) was fed to rats and compared with HFD + simvastatin (10 mg/kg B...

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Bibliographic Details
Main Authors: Zhang Yida, Mustapha Umar Imam, Maznah Ismail, Norsharina Ismail, Nur Hanisah Azmi, Waiteng Wong, Hadiza Altine Adamu, Nur Diyana Md Zamri, Aini Ideris, Maizaton Atmadini Abdullah
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/602313

Internet

http://dx.doi.org/10.1155/2015/602313

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