Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study.

<h4>Background</h4>It has been suggested that greater maternal adiposity during pregnancy affects lifelong risk of offspring fatness via intrauterine mechanisms. Our aim was to use Mendelian randomisation (MR) to investigate the causal effect of intrauterine exposure to greater maternal...

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Bibliographic Details
Main Authors: Rebecca C Richmond, Nicholas J Timpson, Janine F Felix, Tom Palmer, Romy Gaillard, George McMahon, George Davey Smith, Vincent W Jaddoe, Debbie A Lawlor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.1002221