Enhanced lung inflammatory response in whole-body compared to nose-only cigarette smoke-exposed mice

Abstract Background Chronic obstructive pulmonary disease (COPD) is characterized by a progressive and abnormal inflammatory response in the lungs, mainly caused by cigarette smoking. Animal models exposed to cigarette smoke (CS) are used to mimic human COPD but the use of different CS protocols mak...

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Bibliographic Details
Main Authors: Jef Serré, Ajime Tom Tanjeko, Carolien Mathyssen, An-Sofie Vanherwegen, Tobias Heigl, Rob Janssen, Eric Verbeken, Karen Maes, Bart Vanaudenaerde, Wim Janssens, Ghislaine Gayan-Ramirez
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-021-01680-5