Increased Intraepithelial Vα24 Invariant NKT Cells in the Celiac Duodenum

Increased Intraepithelial Vα24 Invariant NKT Cells in the Celiac Duodenum

Celiac Disease (CD) is an interferon (IFN)γ-mediated duodenal hypersensitivity to wheat gluten occurring in genetically predisposed individuals. Gluten-free diet (GFD) leads to a complete remission of the disease. Vα24-restricted invariant NKT (iNKT) cells are important to maintain immune homeostasi...

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Bibliographic Details
Main Authors: Enrique Montalvillo, David Bernardo, Beatriz Martínez-Abad, Yessica Allegretti, Luis Fernández-Salazar, Carmen Calvo, Fernando G. Chirdo, José A. Garrote, Eduardo Arranz
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Nutrients
Subjects:
Celiac Disease
Intraepithelial Lymphocytes
iNKT
Vα24-Jα18
IFNγ
Celiac Disease-like molecular profile
Online Access:http://www.mdpi.com/2072-6643/7/11/5444

Internet

http://www.mdpi.com/2072-6643/7/11/5444

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