Demeanor of rivaroxaban in activated/inactivated FXa

Demeanor of rivaroxaban in activated/inactivated FXa

Activated factor X (FXa) plays an important role in thrombin generation and inflammation. Factor X is not converted constitutively to FXa, but only after intrinsic clotting factors are activated and/or cellular injury occurs. Although rivaroxaban is one of direct FXa inhibitors, its function in the...

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Bibliographic Details
Main Authors: Kaname Seki, Yosuke Mizuno, Toku Sakashita, Shintaro Nakano, Jun Tanno, Yasushi Okazaki, Toshihiro Muramatsu, Shigeyuki Nishimura, Takaaki Senbonmatsu
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Journal of Pharmacological Sciences
Subjects:
Activated factor X
Anticoagulant
Inflammation
Rivaroxaban
Gene modulation
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861317300257

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http://www.sciencedirect.com/science/article/pii/S1347861317300257

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