Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain

<p>Abstract</p> <p>Background</p> <p>We previously reported that intrathecal injection of lysophosphatidylcholine (LPC) induced neuropathic pain through activation of the lysophosphatidic acid (LPA)-1 receptor, possibly via conversion to LPA by autotaxin (ATX).</p>...

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Bibliographic Details
Main Authors: Aoki Junken, Chun Jerold, Inoue Makoto, Nagai Jun, Uchida Hitoshi, Ma Lin, Ueda Hiroshi
Format: Article
Language:English
Published: SAGE Publishing 2009-11-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/5/1/64