Overview on the mechanisms of drug-induced liver cell death

Drug-induced hepatotoxicity is a significant and still unresolved clinical problem. The limitation in current knowledge regarding mechanisms of hepatic toxicity renders most of the preclinical review process failing and most of drug-induced hepatic injury remains unpredictable. Current knowledge on...

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Bibliographic Details
Main Authors: Ignazio Grattagliano, MD, Piero Portincasa, MD PhD, Vincenzo O Palmieri, MD PhD, Giuseppe Palasciano, MD PhD
Format: Article
Published: Elsevier 2002-10-01
Series:Annals of Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S166526811932160X