Overview on the mechanisms of drug-induced liver cell death

Overview on the mechanisms of drug-induced liver cell death

Drug-induced hepatotoxicity is a significant and still unresolved clinical problem. The limitation in current knowledge regarding mechanisms of hepatic toxicity renders most of the preclinical review process failing and most of drug-induced hepatic injury remains unpredictable. Current knowledge on...

Full description

Bibliographic Details
Main Authors: Ignazio Grattagliano, MD, Piero Portincasa, MD PhD, Vincenzo O Palmieri, MD PhD, Giuseppe Palasciano, MD PhD
Format: Article
Language:English
Published: Elsevier 2002-10-01
Series:Annals of Hepatology
Subjects:
Apoptosis
drug-induced liver injury
hepatotoxicity
necrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S166526811932160X

Internet

http://www.sciencedirect.com/science/article/pii/S166526811932160X

Similar Items