Bis(zinc(II)-dipicolylamine)-functionalized sub-2 μm core-shell microspheres for the analysis of N-phosphoproteome

N-phosphorylation plays a critical role in central metabolism and signaling processes, however, enrichment methods for N-phosphopeptides are limited by the P-N bond lability. Here, the authors report the synthesis and use of silica microspheres functionalized with bis(zinc(II)-dipicolylamine) in N-p...

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Bibliographic Details
Main Authors: Yechen Hu, Bo Jiang, Yejing Weng, Zhigang Sui, Baofeng Zhao, Yuanbo Chen, Lukuan Liu, Qiong Wu, Zhen Liang, Lihua Zhang, Yukui Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20026-1