Virtual screening of GPCRs: An <it>in silico</it> chemogenomics approach

<p>Abstract</p> <p>Background</p> <p>The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. <it>In silico </it>prediction of interactions between GPCRs and small molecules in the transmembrane ligand-binding...

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Bibliographic Details
Main Authors: Hoffmann Brice, Jacob Laurent, Stoven Véronique, Vert Jean-Philippe
Format: Article
Language:English
Published: BMC 2008-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/9/363