Mettl14 inhibits bladder TIC self-renewal and bladder tumorigenesis through N 6-methyladenosine of Notch1

Mettl14 inhibits bladder TIC self-renewal and bladder tumorigenesis through N 6-methyladenosine of Notch1

Abstract Background N 6-methyladenosine (m6A) emerges as one of the most important modification of RNA. Bladder cancer is a common cancer type in developed countries, and hundreds of thousands of bladder cancer patients die every year. Materials and methods There are various cells in bladder tumor b...

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Bibliographic Details
Main Authors: Chaohui Gu, Zhiyu Wang, Naichun Zhou, Guanru Li, Yiping Kou, Yang Luo, Yidi Wang, Jinjian Yang, Fengyan Tian
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Molecular Cancer
Subjects:
N 6-methyladenosine
Bladder tumorigenesis
Bladder TIC
Notch1
Mettl14
Self-renewal
Online Access:http://link.springer.com/article/10.1186/s12943-019-1084-1

Internet

http://link.springer.com/article/10.1186/s12943-019-1084-1

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