Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.

Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3.

Half of trauma deaths are attributable to hypovolemic circulatory collapse (HCC). We established a model of HCC in rats involving minor trauma plus severe hemorrhagic shock (HS). HCC in this model was accompanied by a 50% reduction in peak acceleration of aortic blood flow and cardiomyocyte apoptosi...

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Bibliographic Details
Main Authors: Jeffrey A Alten, Ana Moran, Anna I Tsimelzon, Mary-Ann A Mastrangelo, Susan G Hilsenbeck, Valeria Poli, David J Tweardy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2225503?pdf=render

Internet

http://europepmc.org/articles/PMC2225503?pdf=render

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