Treatment of Alzheimer's disease with anti-homocysteic acid antibody in 3xTg-AD male mice.

Alzheimer's disease (AD) is an age-associated progressive neurodegenerative disorder with dementia, the exact pathogenic mechanisms of which remain unknown. We previously reported that homocysteic acid (HA) may be one of the pathological biomarkers in the brain with AD and that the increased le...

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Bibliographic Details
Main Authors: Tohru Hasegawa, Nobuyuki Mikoda, Masashi Kitazawa, Frank M LaFerla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2808336?pdf=render