IgA2 Antibodies against SARS-CoV-2 Correlate with NET Formation and Fatal Outcome in Severely Diseased COVID-19 Patients

IgA2 Antibodies against SARS-CoV-2 Correlate with NET Formation and Fatal Outcome in Severely Diseased COVID-19 Patients

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) leads to an adaptive immune response in the host and the formation of anti-SARS-CoV-2 specific antibodies. While IgG responses against SARS-CoV-2 have been characterized quite well, less is known about IgA. IgA2 activates im...

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Bibliographic Details
Main Authors: Léonie A. N. Staats, Hella Pfeiffer, Jasmin Knopf, Aylin Lindemann, Julia Fürst, Andreas E. Kremer, Holger Hackstein, Markus F. Neurath, Luis E. Muñoz, Susanne Achenbach, Moritz Leppkes, Martin Herrmann, Georg Schett, Ulrike Steffen
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cells
Subjects:
IgA
SARS-CoV-2
COVID-19
inflammation
neutrophil extracellular trap (NET)
Online Access:https://www.mdpi.com/2073-4409/9/12/2676

Internet

https://www.mdpi.com/2073-4409/9/12/2676

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