Overexpression of Wnt7a enhances radiosensitivity of non-small-cell lung cancer via the Wnt/JNK pathway

The Wingless-type protein 7a (Wnt7a) plays an antiproliferative role in non-small-cell lung cancer (NSCLC). Previous studies have indicated that Wnt7a expression was downregulated in radiation-resistant NSCLC cells. However, little is known about its biological functions and molecular mechanisms in...

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Bibliographic Details
Main Authors: Pingping Ai, Xianhua Xu, Shijie Xu, Zhixia Wei, Shun Tan, Junzhe Li
Format: Article
Language:English
Published: The Company of Biologists 2020-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/9/6/bio050575