Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy

The Hippo signaling pathway is a highly-conserved developmental pathway that plays an essential role in organ size control, tumor suppression, tissue regeneration and stem cell self-renewal. The YES-associated protein (YAP) and the transcriptional co-activator with PDZ-binding motif (TAZ) are two im...

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Bibliographic Details
Main Authors: Wen Chun Juan, Wanjin Hong
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/7/9/55