Targeting the Hippo Signaling Pathway for Tissue Regeneration and Cancer Therapy
The Hippo signaling pathway is a highly-conserved developmental pathway that plays an essential role in organ size control, tumor suppression, tissue regeneration and stem cell self-renewal. The YES-associated protein (YAP) and the transcriptional co-activator with PDZ-binding motif (TAZ) are two im...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2016-08-01
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Series: | Genes |
Subjects: | |
Online Access: | http://www.mdpi.com/2073-4425/7/9/55 |