Synergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult Worms.

Treatment and morbidity control of schistosomiasis relies on a single drug, praziquantel (PZQ), and the selection of resistant worms under repeated treatment is a concern. Therefore, there is a pressing need to understand the molecular effects of PZQ on schistosomes and to investigate alternative or...

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Main Authors: Giulliana T Almeida, Regina C G Lage, Leticia Anderson, Thiago M Venancio, Helder I Nakaya, Patrícia A Miyasato, Henrique K Rofatto, Adhemar Zerlotini, Eliana Nakano, Guilherme Oliveira, Sergio Verjovski-Almeida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4581627?pdf=render