EGFR signaling suppresses type 1 cytokine-induced T-cell attracting chemokine secretion in head and neck cancer.

EGFR signaling suppresses type 1 cytokine-induced T-cell attracting chemokine secretion in head and neck cancer.

Resistance to antitumor immunity can be promoted by the oncogenic pathways operational in human cancers, including the epidermal growth factor receptor (EGFR) pathway. Here we studied if and how EGFR downstream signaling in head and neck squamous cell carcinoma (HNSCC) can affect the attraction of i...

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Bibliographic Details
Main Authors: Wenbo Ma, Fernando Concha-Benavente, Saskia J A M Santegoets, Marij J P Welters, Ilina Ehsan, Robert L Ferris, Sjoerd H van der Burg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6128559?pdf=render

Internet

http://europepmc.org/articles/PMC6128559?pdf=render

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