Novel 4-aminoquinazoline derivatives as new leads for anticancer drug discovery

A novel series of quinazoline derivatives 2-8, 10-12 were designed and synthesized. Structures of the newly synthesized compounds were confirmed by elemental analyses, IR, 1H and 13C NMR spectral data. All the newly synthesized compounds were evaluated for in vitro cytotoxic activity against the bre...

Full description

Bibliographic Details
Main Authors: Ghorab Mostafa M., Alsaid Mansour S.
Format: Article
Language:English
Published: Sciendo 2015-09-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.1515/acph-2015-0021