The Pseudomonas aeruginosa Orphan Quorum Sensing Signal Receptor QscR Regulates Global Quorum Sensing Gene Expression by Activating a Single Linked Operon

The Pseudomonas aeruginosa Orphan Quorum Sensing Signal Receptor QscR Regulates Global Quorum Sensing Gene Expression by Activating a Single Linked Operon

Pseudomonas aeruginosa uses two acyl-homoserine lactone signals and two quorum sensing (QS) transcription factors, LasR and RhlR, to activate dozens of genes. LasR responds to N-3-oxo-dodecanoyl-homoserine lactone (3OC12-HSL) and RhlR to N-butanoyl-homoserine lactone (C4-HSL). There is a third P. ae...

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Bibliographic Details
Main Authors: Fengming Ding, Ken-Ichi Oinuma, Nicole E. Smalley, Amy L. Schaefer, Omar Hamwy, E. Peter Greenberg, Ajai A. Dandekar
Format: Article
Language:English
Published: American Society for Microbiology 2018-08-01
Series:mBio
Subjects:
acyl-homoserine lactone
antiactivation
sociomicrobiology
Online Access:https://doi.org/10.1128/mBio.01274-18

Internet

https://doi.org/10.1128/mBio.01274-18

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