Improper Remodeling of Organelles Deputed to Ca<sup>2+</sup> Handling and Aerobic ATP Production Underlies Muscle Dysfunction in Ageing

Improper Remodeling of Organelles Deputed to Ca<sup>2+</sup> Handling and Aerobic ATP Production Underlies Muscle Dysfunction in Ageing

Proper skeletal muscle function is controlled by intracellular Ca<sup>2+</sup> concentration and by efficient production of energy (ATP), which, in turn, depend on: (a) the release and re-uptake of Ca<sup>2+</sup> from sarcoplasmic-reticulum (SR) during excitation–contraction...

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Bibliographic Details
Main Authors: Feliciano Protasi, Laura Pietrangelo, Simona Boncompagni
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
Ca<sup>2+</sup> entry unit (CEU)
Ca<sup>2+</sup> release unit (CRU)
excitation–contraction (EC) coupling
mitochondria
sarcoplasmic-reticulum (SR)
store-operated Ca<sup>2+</sup> entry (SOCE)
Online Access:https://www.mdpi.com/1422-0067/22/12/6195

Internet

https://www.mdpi.com/1422-0067/22/12/6195

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