Cytoskeleton Rearrangements Modulate TRPC6 Channel Activity in Podocytes

Cytoskeleton Rearrangements Modulate TRPC6 Channel Activity in Podocytes

The actin cytoskeleton of podocytes plays a central role in the functioning of the filtration barrier in the kidney. Calcium entry into podocytes via TRPC6 (Transient Receptor Potential Canonical 6) channels leads to actin cytoskeleton rearrangement, thereby affecting the filtration barrier. We hypo...

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Bibliographic Details
Main Authors: Alexey Shalygin, Leonid S. Shuyskiy, Ruslan Bohovyk, Oleg Palygin, Alexander Staruschenko, Elena Kaznacheyeva
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
podocyte
focal segmental glomerulosclerosis
FSGS
TRPC6
actin cytoskeleton
α-actinin-4
Online Access:https://www.mdpi.com/1422-0067/22/9/4396

Internet

https://www.mdpi.com/1422-0067/22/9/4396

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