The HSP70 modulator MAL3-101 inhibits Merkel cell carcinoma.

Merkel Cell Carcinoma (MCC) is a rare and highly aggressive neuroendocrine skin cancer for which no effective treatment is available. MCC represents a human cancer with the best experimental evidence for a causal role of a polyoma virus. Large T antigens (LTA) encoded by polyoma viruses are oncoprot...

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Bibliographic Details
Main Authors: Christian Adam, Anne Baeurle, Jeffrey L Brodsky, Peter Wipf, David Schrama, Jürgen Christian Becker, Roland Houben
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3973671?pdf=render