T1AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex

Abnormalities in thyroid hormones (TH) availability and/or metabolism have been hypothesized to contribute to Alzheimer's disease (AD) and to be a risk factor for stroke. Recently, 3-iodothyronamine (T1AM), an endogenous amine putatively derived from TH metabolism, gained interest for its abili...

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Bibliographic Details
Main Authors: Francesca Tozzi, Grazia Rutigliano, Marco Borsò, Chiara Falcicchia, Riccardo Zucchi, Nicola Origlia
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121000206